Lupinosis is a liver disease mainly caused by the consumption of lupin stalks (or seeds) colonised by the fungus Diaporthe toxica. It can be expressed as either a severe acute disease or as a chronic liver dysfunction syndrome. Chronic lupinosis is commonly associated with narrow-leafed lupin stubbles or when lupin seed is fed. Lupinosis may also predispose sheep to a nutritional muscle disease (myopathy) called lupinosis-associated myopathy.
